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2007-07-25-09 Agenesis of the corpus callosum © Cuillier www.thefetus.net/
Agenesis of the corpus callosum

Fabrice Cuillier, MD*; L. Lagarde, MD**.

*  Department of Gynecology, Felix Guyon Hospital, 97400 Saint- Denis, Ile de la Reunion, France; tel: 0262 90 55 22; fax : 0262 90 77 30;
** Department of Gynecology, Gabriel Martin’Hospital, 97400 Saint-Denis, Ile de la Réunion.

 

Case report

A 35-year-old G5P4, referred to our antenatal unit at 35 weeks. Her first trimester screening was normal. The second trimester ultrasound wasn"t practiced. Our investigation revealed bilateral ventriculomegaly (14 mm) with agenesis of the corpus callosum. The pericallosal artery could not be identified and the MRI confirmed the diagnosis. No associated anomalies were seen and the karyotype and serological tests (Toxoplasmosis, Rubeola, CMV, Herpes, and Chikungunya) were also normal. The patient delivered at 37 weeks of pregnancy and the diagnosis was confirmed.

Images 1, 2: Transverse images of the fetal head showing ventriculomegaly with characteristic "tear drop" configuration of the lateral ventricles.

 

Images 3, 4: Sagittal color Doppler images were not able to detect the pericallosal artery.

 

Images 5, 6: MRI images showing dilated lateral cerebral ventricles and absence of the corpus callosum.

 

 

 

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