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Articles » Central nervous system » Agenesis of the corpus callosum
2006-05-30-14 Agenesis of the corpus callosum © Cuillier www.thefetus.net/  

Agenesis of the corpus callosum

Cuillier F, MD*, Lemaire P**, Deshayes M**

*  Department of Gynecology, Félix Guyon"Hospital  **   Sonographer, Moufiastreet, Ile de la Réunion

Case report: This is a 30-year-old-woman, primigravida, referred to our antenatal unit at 24 weeks. The first trimester screening was normal (nuchal translucency and triple test). At 23 weeks, a bilateral ventriculomegaly (11 mm) with agenesis of corpus callosus were suspected. No associated anomalies were seen.  At 24 weeks, the ventriculomegaly (lateral ventricles = 12 mm) was confirmed. The karyotype was normal. The serological tests were normal (toxoplasmosis, rubeola, CMV, herpes). At 26 weeks, the lateral ventricles were measuring 12 mm. The pericallosal artery could not be identified. The parents were counseled and decided to continue the pregnancy. At 27 weeks, the lateral ventricles were 13 mm. At 32 weeks, a MRI was performed and confirmed the diagnosis. The delivery ocurred at 38 weeks. At the end of the third month, the baby was normal and a serial transfontanellar examination confirmed the diagnosis.

 

Note the bilateral ventriculomegaly

The corpus callosum and the pericallosal artery could not be identified

MRI images